Abstract Background Unresectable or metastatic vulvar cancer has relatively poor outcomes despite chemotherapy-sensitized radiation therapy and combination cytotoxic therapy.Despite the virus-associated and immunogenic nature of this disease, CARDIGANS novel immunotherapy options that exploit this advantage are currently lacking.Platinum agents suc
ObjectiveTo report the first use of a novel projected augmented reality (AR) system in open sinonasal tumor resections in preclinical models and to Lanyard compare the AR approach with an advanced intraoperative navigation (IN) system.MethodsFour tumor models were created.Five head and neck surgeons participated in the study performing virtual oste
Hibernating mammals drastically lower their metabolic rate (MR) and body temperature (Tb) for up to several weeks, but regularly rewarm and stay euthermic for brief periods.It has been hypothesized that the necessity for rewarming is due to the accumulation or depletion of metabolites, or the accrual of cellular damage Eddy Brake that can be elimin
The modern infirmary is the evolutional product of the dialectic interface between medical theories at each time and the outcome of their application in clinical practice.The infirmary as we know it today did not exist during antiquity, but the different precursors of the modern hospital emerged as a result of the interaction between medical theory